Thus, the hippocampus helps connect memories to the emotions experienced when the memories form.

read more, which controls the experience and expression of emotions. Which side of the brain is affected is also important. The hippocampus is part of the limbic system Limbic Lobe Damage Because different areas of the brain control specific functions, the location of brain damage determines the type of dysfunction that results. For example, the hippocampus, located deep within the brain, is involved in the formation of new memories and retrieval of stored memories.

read more, but many areas of the brain are involved in memory. read more and frontal lobe Frontal Lobe Damage Because different areas of the brain control specific functions, the location of brain damage determines the type of dysfunction that results. doi:10.The brain’s mechanisms for storing information and recalling it from memory are located primarily in the temporal lobe Temporal Lobe Damage Because different areas of the brain control specific functions, the location of brain damage determines the type of dysfunction that results. Acute-Onset Amnesia: Transient Global Amnesia and Other Causes. What Does Transient Global Amnesia Really Mean? Review of the Literature and Thorough Study of 142 Cases. Quinette P, Guillery-Girard B, Dayan J et al. Transient Global Amnesia: Diffusion-Weighted Imaging Lesions and Cerebrovascular Disease. Optimal Diffusion-Weighted Imaging Protocol for Lesion Detection in Transient Global Amnesia. High-Resolution Diffusion-Weighted Imaging Increases Lesion Detectability in Patients with Transient Global Amnesia. This confused state isn't caused by a more common neurological condition, such as epilepsy or stroke. doi:10.1016/S0140-6736(11)61304-4 - Pubmed Overview Transient global amnesia is an episode of confusion that comes on suddenly in a person who is otherwise alert. Post-traumatic amnesia, has a history of trauma 6 Psychogenic amnesia, more-so affects semantic memory compared to episodic memory, while TGA is the opposite 6ĭrug-related amnesia, typically has features of encephalopathy 6 Transient epileptic amnesia, typically presents upon waking while TGA does not 6 Transient global amnesia (TGA) is a clinical syndrome characterized by reversible anterograde amnesia, in which the patient is alert, self-awareness appears intact and other neurological symptoms. hippocampal ischaemic), typically exists with other neurological deficits 6

The condition rarely recurs in ~5% of patients 5,6. These changes generally appear after symptom resolution, and the highest rate of detection is approximately 2 days after symptom onset 6. These lesions can be bilateral and even multifocal 2-4. Prospective and retrospective studies based on a small number of transient global amnesia patients can detect small punctate regions of abnormally restricted diffusion on DWI/ADC sequences in the CA1 area of the hippocampus (lateral edge of the hippocampal gyrus abutting the temporal horn). Radiographic featuresĬT brain and conventional sequences of MRI brain may show no abnormalities, especially while the patient is symptomatic. epileptic phenomena, stroke, focal ischaemia) have been proposed with no consensus on the exact mechanism 1,6. Most cases show complete resolution of symptoms within a few hours from onset of symptoms 6. Episodic memories are more-so affected than semantic memories 6. AssociationsĪnterograde and partial retrograde amnesia lasting less than 24 hours without any other neurological or congestive symptoms 6. Transient global amnesia is most common in the 50-70 year age range ref.

Global amnesia event